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CNSTREAM: A METHOD FOR THE IDENTIFICATION AND GENOTYPING OF COPY NUMBER POLYMORPHISMS USING ILLUMINA MICROARRAYS

CNstream is a useful method for the identification and characterization of CNPs using Illumina genotyping microarrays. Compared to the PennCNV method, it has greater sensitivity over multiple CNP loci and allows more powerful statistical analysis in these regions. Therefore, CNstream is a robust CNP analysis tool of use to researchers performing genome-wide association studies (GWAS) on Illumina platforms and aiming to identify CNVs associated with the variables of interest. CNstream has been implemented as an R statistical software package that can work directly from raw intensity files generated from Illumina GWAS projects.

Alonso A, Julià A, Tortosa R, Canaleta C, Cañete JD, Ballina J, Balsa A, Tornero J, Marsal S. CNstream: A method for the identification and genotyping of copy number polymorphisms using Illumina microarrays. BMC Bioinformatics . 2010 May 19;11:264.

Package Source CNstream_1.0.tar.gz

Windows Binary CNstream_1.0.zip

Tutorial

CNStream workflow