The AIRR study in rheumatoid arthritis
AIRR Analyses
Diversity
Case-Control
Case-Case
Longitudinal
Contraction/Expansion
Overview
Frequency Variation
CDR3aa similarity
Biochemical profile
Chain Usage
Case-Control
Case-Case
Longitudinal
Gene Segment Usage
Case-Control
Case-Case
Longitudinal
Clone publicity
Case-Control
Case-Case
Longitudinal
Single-clone
Case-Control
Case-Case
Meta-clone
Analytical approach
Case-Control
Case-Case
K-mer
Case-Control
Case-Case
HLA-TRB clusters
TRB cluster enrichment
RA-specific TRB clusters associated with HLA
Genetic risk to RA
CDR3aa seq length
Case-Control
Case-Case
Longitudinal
Isotype Signature
Isotype Percentage
Isotype Class Switching
Somatic Hypermutations
Mutated IgD/M
Multi-chain predictor
AIRR predictors
Rheumatoid arthritis
Clinical Phenotypes
GitHub
Download
AIRR RA
Chain usage analysis: case-control results
Summary
Whole Blood
Synovial Tissue
Data source:
Lewis MJ et al ’19
A work by
GRR
. All rights reserved.
